The dietary supplements from Lab de l'Endo

At Le Lab de l'Endo, our range of products is divided into 2 categories:

• Care for relief
• Dietary supplements to target

Our research work revolves around the study of the 5 pathophysiological mechanisms of endometriosis, involved in the development/reduction of symptoms. (You can find the corresponding article on the Blog.)

Here are some explanations about our following dietary supplements:

1. The PEA - Premium - OptiPEA®
2. The probiotics 9 Strains - Saffron 
3. The SPM treatment - Saffron'inside'
4. The ZMA+ Complex Premium (Magnesium Zinc Vit B6)
5. Vitamin D3 - 2000 IU
6. Omega 3 - 1000 mg

That you can complement with the Sleep cure, if you wish to enhance the reduction of your chronic fatigue, with restorative sleep:

6. Sleep Synergy CBD Melatonin - 1500mg

Reminder of the usage tips for our supplements:

How can our range of supplements help you target the cause of your symptoms? 

1. The PEA Premium - OptiPEA®

• Scientific explanation:

L'OptiPEA® or palmitoylethanolamide, in its full name, is the most interesting nutraceutical you've never heard of! It is recognized as an effective solution for managing chronic (menstrual, digestive) and neuropathic pain. Thanks to its natural anti-inflammatory, it helps to calm chronic pain, while modulating the immune system's response to alleviate chronic inflammation.

Supported by more than 700 scientific articles, 60 medical indications for use, and 60 years of research, PEA is a natural compound that offers compelling benefits for pain relief.

2. Probiotics 9 strains - Saffron

• Scientific explanation:

This supplement combines essential probiotics to support your gut microbiota, reduce your inflammation, and intestinal dysbiosis.

Coupled with a relevant concentration of saffron to soothe anxiety, in order to support the gut-brain axis, our formulation targets the reduction of your digestive issues, while also targeting the reduction of your anxiety, which is all the more productive, as the two are linked. 

If we summarize the action of our formulation:

• 9 probiotic strains: ↘️ Dysbiosis ↘️ Intestinal permeability ↘️ Inflammation ↘️ Digestive symptoms (endobelly, bloating, constipation, diarrhea...) ↘️ Fatigue
• Lactobacillus and Bifidobacterium Strains: ↘️ Stress, anxiety, depression
• 30 mg Saffron: ↘️ PMS, PMDD, Antidepressant action, analgesic & antioxidant
• L Gasseri Strains: ↘️ Inflammation ↘️ Bloating ↘️ Constipation ↘️ Slow digestion ↘️ Anxiety

• Simplified explanation:

Our 9-strain probiotics - Safran, will help relieve your digestive issues (bloating, endobelly, constipation, diarrhea...), your anxiety, but also your inflammation, therefore all associated symptoms (menstrual, digestive, neuropathic pain, chronic fatigue...). Our concentration of Saffron can also provide a boost to libido, which is not the main goal of this probiotic, but has been reported to us by several clients.

• Why is our product the most high-quality?

Our probiotics are based on numerous clinical studies, offering the first formulation designed for women's health and endometriosis, through its unique concentration of Saffron.

The reviews from our customers speak for themselves :)

3. The PMS / anxiety treatment

• Scientific explanation:

The effectiveness of our patented saffron Safr'Inside™ on premenstrual syndrome was evaluated in an open study* under the supervision of a gynecologist, using a self-assessment questionnaire. The level of discomfort from the psychological and physical symptoms of premenstrual syndrome was assessed by the participants before and after each supplementation cycle.

95% felt a improvement of emotional balance as well as a reduction in irritability.

85% experienced a reduction in their emotionality as well as a decrease in their nervousness.

• Simplified explanation:

The PMS / Anxiety treatment will help you reduce your anxiety, emotionality, irritability, fatigue, and physical pain throughout your cycle, and especially before your period, thanks to the natural antidepressant effects of our patented saffron.

• Why is our product the most high-quality?

The saffron we use is highly concentrated and derived from a patented technology, ensuring that you benefit from all its natural components in their most effective form.

The reviews from our customers speak for themselves :)

4. The ZMA+ Premium complex (Magnesium bisglycinate, zinc, vit B6)

• Scientific explanation:

There are many forms of minerals and not all are equivalent in terms of assimilation and benefits for the body, which is why we have chosen "bisglycinate" for MAGNESIUM and ZINC, not forgetting our B6 which is in its pyridoxal form: the Bioactive form of vitamin B6.

This supplementation aims to support the proper functioning of your immune system, protect your cells from oxidative stress, support hormonal activity, and promote the optimal functioning of the nervous system.

• Simplified explanation:

Magnesium often becomes deficient in cases of chronic stress, the same goes for zinc which has an essential antioxidant action in female hormonal health, and the same for vit B6.

This supplement will support you in the fight against anxiety, fatigue, and chronic pain. 

• Why is our product the most high-quality?

Studies recommend:

- between 200 mg to 400 mg of magnesium / day, which corresponds to approximately 1,000 mg to 2,000 mg of magnesium bisglycinate / day ; 

- between 20 to 30 mg per day for zinc;

- and about 10 to 50 mg per day for the active form of vitamin B6, the Pyridoxal phosphate (P5P)

--> Our supplement offers 1250mg Magnesium bisglycinate 50mg Zinc bisglycinate, and 1 400mg vit B6 Pyridoxal phosphate

--> to ensure the best assimilation, intestinal tolerance, and highest bioavailability. 

5. Vitamin D3 - 2000 IU

• Scientific explanation:

Vitamin D supplementation is widely recommended if you suffer from chronic fatigue, as is often the case with endometriosis. The sign of a vitamin D deficiency is often linked to fatigue, lack of energy, and muscle weakness, so it is recommended to choose the most assimilable form: vitamin D3 as it is naturally found in fatty fish or dairy products is the most stable active form and the closest to the vitamin D molecule that we produce ourselves.

• Simplified explanation:

Supplementing with vitamin D3 will help you fight against your chronic fatigue, lack of energy, and depressive mood.

• Why is our product the most high-quality?

Studies prove that the concentration in IU is insignificant below 1000 IU/day, especially in cases of deficiency such as with an inflammatory disease like endometriosis:

-->  that's why our Vit D3 is equivalent to 2000 IU / Spray !

6. Omega 3 - 1000 mg 

• Scientific explanation:

Omega-3 are essential fatty acids, recognized for their powerful anti-inflammatory properties. They play a crucial role in reducing chronic inflammation, often associated with pain related to endometriosis. Omega-3, particularly in their EPA (eicosapentaenoic acid) and DHA (docosahexaenoic acid) forms, work by inhibiting the production of pro-inflammatory molecules in the body.

Omega-3 supplementation helps restore the balance between omega-6 (pro-inflammatory) and omega-3 (anti-inflammatory) in the body.

• Simplified explanation:

Omega-3s will help your body reduce inflammation, which means less chronic pain (menstrual, digestive, neuropathic...) and more energy! and an overall improvement in your well-being.  

• Why is our product the most high-quality?

Studies show that doses exceeding 1000 mg per day of combined EPA and DHA are effective in reducing inflammation.

--> Our supplement offers 1200 mg per day!

Sources:

- Palmitoylethanolamide (PEA) in the treatment of chronic pain: systematic review and meta-analysis of double-blind randomized controlled trials: https://www.mdpi.com/2072-6643/15/6/1350

- Clinical applications of palmitoylethanolamide (PEA) in pain management: protocol of an exploratory study: https://systematicreviewsjournal.biomedcentral.com/articles/10.1186/s13643-018-0934-z

- The link between the brain and the gut: https://www.hopkinsmedicine.org/health/wellness-and-prevention/the-brain-gut-connection

- Regulating gut bacteria could relieve anxiety: https://www.sciencedaily.com/releases/2019/05/190520190110.htm

- What is the link between anxiety and gut health? : https://patient.info/news-and-features/whats-the-link-between-anxiety-and-gut-health